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ESCOZUL analgesic activity




The graphic shows the results of an experimental model of chemical analgesia. Six groups of laboratory mice subjected to different concentrations of ESCOZUL were examined, a control (+) group subjected to ASA and a control (-) group without any analgesic. The mice were induced pain by injecting acetic acid into them after which the specialists counted the number of contortions the mice suffered in a period of 10 minutes. The number of contortions is a pain indicator. The different letters inside the bars indicate significant statistical differences in the number of contortions between treatments. On the contrary, the treatments with equal letters indicate there are no differences between them. Thus, it can be observed that ESCOZUL has analgesic activity and that there are no differences between the treatment effects with ASA, 5, 10, 15, 20 and 50 mg/Kg of ESCOZUL. The graphic shows the inhibition percentage of the contortions for each treatment. It can be seen in the graphic that the treatments with high concentrations of ESCOZUL can inhibit up to 55% of pain. This experiment with mice could explain why cancer patients who are treated with ESCOZUL show a pain reduction.