The graphic shows the results of an experimental model of
chemical analgesia. Six groups of laboratory mice subjected to different concentrations
of ESCOZUL were examined, a control (+) group subjected to ASA and a control
(-) group without any analgesic. The mice were induced pain by injecting acetic
acid into them after which the specialists counted the number of contortions
the mice suffered in a period of 10 minutes. The number of contortions is
a pain indicator. The different letters inside the bars indicate significant
statistical differences in the number of contortions between treatments. On
the contrary, the treatments with equal letters indicate there are no differences
between them. Thus, it can be observed that ESCOZUL has analgesic activity
and that there are no differences between the treatment effects with ASA,
5, 10, 15, 20 and 50 mg/Kg of ESCOZUL. The graphic shows the inhibition percentage
of the contortions for each treatment. It can be seen in the graphic that
the treatments with high concentrations of ESCOZUL can inhibit up to 55% of
pain. This experiment with mice could explain why cancer patients who are
treated with ESCOZUL show a pain reduction.
